Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery

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Acute kidney injury following cardiac surgery.

Acute kidney injury (AKI), a recognized complication of cardiac surgery with cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality (15-30%) with approximately 1% of all the affected patients requiring dialysis. Early detection of AKI would enable intervention before occurrence of irreversible injury and might minimize the morbidity and mortality. Recently developed b...

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MicroRNA-21 and Risk of Severe Acute Kidney Injury and Poor Outcomes after Adult Cardiac Surgery

BACKGROUND Severe acute kidney injury (AKI) after cardiac surgery is associated with poor clinical outcomes. This study evaluated the potential use of miR-21 as a risk marker for postoperative AKI progression and other poor outcomes. METHODOLOGY/PRINCIPAL FINDINGS The study included 120 adult patients undergoing cardiac surgery: 40 non-AKI controls, 39 patients with progressive AKI, and 41 wi...

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Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery.

Acute kidney injury (AKI) is a frequent complication of cardiac surgery and increases morbidity and mortality. The identification of reliable biomarkers that allow earlier diagnosis of AKI in the postoperative period may increase the success of therapeutic interventions. Here, we conducted a prospective, multicenter cohort study involving 1219 adults undergoing cardiac surgery to evaluate wheth...

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Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery.

Acute kidney injury (AKI) occurs commonly after pediatric cardiac surgery and associates with poor outcomes. Biomarkers may help the prediction or early identification of AKI, potentially increasing opportunities for therapeutic interventions. Here, we conducted a prospective, multicenter cohort study involving 311 children undergoing surgery for congenital cardiac lesions to evaluate whether e...

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Acute Kidney Injury Following Cardiac Surgery: Prevention, Diagnosis, and Management

Acute kidney injury (AKI) following cardiac surgery is associated with increased morbidity and mortality, longer hospital stays, and significantly increased health care costs. The physiological functions performed by the kidney, which include acid-base control, blood pressure regulation, water balance, and waste excretion, are crucial to the maintenance of homeostasis and can only partially be ...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2018

ISSN: 2045-2322

DOI: 10.1038/s41598-018-20212-8